The Cross Hotel Osaka is one of many Osaka hotels that is centrally located and near many popular Osaka attractions such as the Namba area, which is widely known for its Kabuki Theater, and the Osaka Castle. The Cross Hotel Osaka is located at 2-5-15 Shinsaibashisuji in Osaka, Japan. The site is located on Midosuji Avenue. This site is five kilometers from the Osaka railway station and 54 kilometers from the airport.

The Cross Hotel Osaka has 227 rooms all modernly decorated and furnished. Rooms at the hotel include irons, trouser presses, hairdryers and safes. All rooms are air-conditioned. Guests can expect work desks, large spacious areas in their rooms, satellite TV and Internet access. Some rooms also have a refrigerator.

There are three on-site restaurants at the Cross Hotel Osaka, serving Japanese or Western food. There is also an on-site bar as well a fitness center and gym. This is a four-star hotel. It was first built in 1975 but last renovated in 2007.